Multidrug

A research study led by the University of Oxford provides a transformational new insight into how antimicrobial resistance (AMR) emerges in patients with bacterial infections. The findings, published today in the journal Nature…

The World Health Organization lists bacteria that are resistant to antibiotics as one of the top 10 global health threats. Therefore, researchers are looking for new antibiotics to counter this resistance. Adéla Melcrová, biophysicist at…

Treating cancer with combinations of drugs can be more effective than using a single drug. However, figuring out the optimal combination of drugs, and making sure that all of the drugs reach the right place, can be challenging. To help…

One of the greatest challenges facing cancer researchers is to understand why some patients don't respond to treatments. In some cases, tumors exhibit what is known as multidrug resistance (MDR), which significantly limits the therapeutic…

SPR206 shown to be well-tolerated; achieved lung exposures consistent with predicted therapeutic levels, when administered three times daily at 100 mg Results support further development of SPR206 in the setting of hospital-acquired…