CRISPRbased

Many genetic diseases are caused by diverse mutations spread across an entire gene, and designing genome editing approaches for each patient's mutation would be impractical and costly. Investigators at Massachusetts General Hospital (MGH)…

Serum TTR reductions were sustained at all doses tested with follow-up now reaching 12 months in the 0.1 and 0.3 mg/kg and six months in the 0.7 and 1.0 mg/kg cohorts Pharmacokinetic modeling and simulation indicated that an 80 mg fixed…

A genome-editing strategy developed at Rice University can correct dozens of errors at the same time with high precision and efficiency, a possible breakthrough for those who suffer from diseases caused by a combination of mutations. The…

Blending experts from molecular genetics, chemistry and health sciences, researchers at the University of California San Diego have created a rapid diagnostic technology that detects SARS-CoV-2, the coronavirus that causes COVID-19. The new…

The team led by Dr. Stephen Elledge at Harvard Medical School and Brigham and Women's Hospital, Boston, has published the research online in Molecular Cell today (13 August). The paper's first author, Dr. Karl Barber, is a 2018 Schmidt…