Due to BBB, achieving the delivery of this ASO therapy with systemic dosing and adequate concentrations in the central nervous system (CNS) has been difficult. ‘Specific group of drugs antisense oligonucleotides (ASOs) are found to…
ACE inhibitors, angiotensin II receptor blockers (ARBs), calcium channel blockers and diuretics are different classes of blood pressure-lowering medicines. Each class acts in a different way to reduce blood pressure, and some cross the…
First, the research team investigated whether cholesterol catabolism was associated with brain abnormalities typical of Alzheimer's and vascular dementia. They next tested whether exposure to cholesterol medications that block bile acid…