Alpha-1 Antitrypsin Deficiency (A1ATD) Liver Disease Pipeline: Insights into New Pipeline Therapies and Landscape; Future Key Pharma Companies and Novel Therapeutic Assessment

Los Angeles, USA, Aug. 12, 2021 (GLOBE NEWSWIRE) — Alpha-1 Antitrypsin Deficiency Liver Disease Pipeline: Insights into New Pipeline Therapies and Landscape; Future Key Pharma Companies and Novel Therapeutic Assessment

Alpha-1 Antitrypsin Deficiency Liver Disease Pipeline is in its nascent budding stage with novel molecules targeting new therapeutic targets.

DelveInsight’s ‘Alpha-1 Antitrypsin Deficiency (A1ATD) Liver Disease Pipeline Insight report provides comprehensive insights to Alpha-1 Antitrypsin Deficiency Liver Disease pipeline therapies and key companies involved in the production. The available marketed therapies in A1ATD Liver Disease pipeline in different phases of clinical development, comparative analysis and future growth potential of the A1ATD Liver Disease pipeline territory. Overview of A1ATD Liver Disease including its Causes, Symptoms, Risk Factors, Pathophysiology, Diagnosis and Treatment are covered. The report also builds an understanding of the limitations and challenges in the field of Alpha-1 Antitrypsin Deficiency Liver Disease.

Some of the key highlights from the Alpha-1 Antitrypsin Deficiency Liver Disease Pipeline report:

• DelveInsight’s analysis presents Alpha-1 Antitrypsin Deficiency Liver Disease Pipeline with 10+ active players in the domain investigating 10+ pipeline therapies. 
• Many key companies such as Apic Bio, Centessa Pharmaceuticals, Dicerna Pharmaceuticals, PH Pharmaceutical, Arrowhead Pharmaceuticals, Alnylam Pharmaceuticals, and others are proactively engaged in the development of the potential drug candidates to improve the ongoing Alpha-1 Antitrypsin Deficiency Liver Disease treatment.
• Emerging Alpha-1 Antitrypsin Deficiency Liver Disease Pipeline therapies such as APB-101, ZF874, Belcesiran, PHP 303, ARO-AAT, ALN-AAT02, and others are under investigation in different phases of clinical trials.
• In July 2021, Arrowhead Pharmaceuticals announced that it was granted Breakthrough Therapy designation (BTD) by the US FDA for ARO-AAT, also known as TAK-999, being co-developed with Takeda Pharmaceutical Company as a treatment for the rare genetic liver disease associated with alpha-1 antitrypsin deficiency (AATD).
• In July 2021, Dicerna Pharmaceuticals announced interim results from the four completed active-treatment dose cohorts (0.1, 1.0, 3.0 and 6.0 mg/kg) of its Phase I double-blind, placebo-controlled, randomized trial of belcesiran, an investigational GalXC™ RNAi therapeutic in development for the treatment of alpha-1 antitrypsin deficiency-associated liver disease (AATLD).

Request for Sample to know which pharmaceutical company is expected to be at the forefront in the coming years @Alpha-1 Antitrypsin Deficiency Liver Disease Pipeline Therapies and Forecast 

The Alpha-1 Antitrypsin Deficiency Liver Disease pipeline report puts forward detailed profiles of the pipeline assets along with the inactive and dormant assets, comparative analysis of clinical and non-clinical stage Alpha-1 Antitrypsin Deficiency (A1ATD) Liver Disease products, comprehensive assessment of driving and restraining factors along with the opportunities and risks in the Alpha-1 Antitrypsin Deficiency Liver Disease pipeline landscape.

Alpha-1 Antitrypsin Deficiency Liver Disease Overview

Alpha-1 Antitrypsin Deficiency (A1ATD) Liver Disease, is an inherited metabolic disorder in which this protein is absent or defective. The deficiency is a result of a mutation in the A1AT protein encoding gene SERPINA1 and is inherited in an autosomal recessive manner. Alpha-1 antitrypsin is a large, 52‐kDa serum glycoprotein and a serine protease inhibitor.

Alpha-1 Antitrypsin Deficiency Liver Disease Pipeline Drugs

Request for Sample to know more @ Alpha-1 Antitrypsin Deficiency Liver Disease Pipeline Analysis, Key Companies, and Futuristic Trends 

Alpha-1 Antitrypsin Deficiency Liver Disease Therapeutics Assessment

The Alpha-1 Antitrypsin Deficiency Liver Disease Pipeline report proffers an integral view of the Alpha-1 Antitrypsin Deficiency Liver Disease emerging novel therapies segmented by Stage, Product Type, Route of Administration, Molecule Type, Target, and Mechanism of Action.

By Product Type

By Stage

• Discovery 
• Pre-clinical
• Phase I
• Phase II
• Phase III
• Pre-registration

By Route of Administration

• Subcutaneous
• Intravenous
• Oral
• Inhalation

By Molecule Type 

• Gene therapy
• Stem cell therapy
• Small molecules
• RNAi Molecule

By Mechanism of Action

• Gene transference
• Alpha 1 antitrypsin modulators
• Neutrophil elastase (NE) inhibitor
• Sodium channel antagonists

By Targets

• Alpha 1 antitrypsin
• Neutrophil elastase
• Sodium channel

Scope of the Alpha-1 Antitrypsin Deficiency Liver Disease Pipeline Report 

• Coverage: Global 
• Major Players: Apic Bio, Centessa Pharmaceuticals, Dicerna Pharmaceuticals, PH Pharmaceutical, Arrowhead Pharmaceuticals,  LogicBio Therapeutics, Alnylam Pharmaceuticals.
• Key Alpha-1 Antitrypsin Deficiency Liver Disease Pipeline Theraṣpies: APB-101, ZF874, Belcesiran, PHP 303, ARO-AAT, LB 201, ALN-AAT02.

For deep insights into emerging therapies and assessment, request @ A1ATD Liver Disease Pipeline Emerging Novel Therapies 

Table of Contents 

Discover more about the scope of the report @ Alpha-1 Antitrypsin Deficiency Liver Disease Emerging Therapies, Treatments, and Ongoing Clinical Trials 

Related Reports

Non Alcoholic Fatty Liver Disease Market

DelveInsight’s “Non Alcoholic Fatty Liver Disease (NAFLD) – Market Insights, Epidemiology, and Market Forecast-2030” report

Acute Lung Injury Pipeline

“Acute Lung Injury Pipeline Insights, 2021” report by DelveInsight

Interstitial Lung Disease Market 

DelveInsight’s “Interstitial Lung Disease – Market Insights, Epidemiology, and Market Forecast-2030” report                             

Browse Through Our Blog Posts

Small Cell Lung Cancer Market Booms with an Influx of Companies and Robust Pipeline
As per DelveInsight, the Small cell lung cancer market size is anticipated to increase at a CAGR of 15.2% during the study period (2017–30) owing to a robust pipeline, healthcare spending, improved R&D, and discovery of novel targets.

Novel mutation-targeting therapies on the horizon to relieve the global healthcare burden NSCLC poses
The non-small cell lung cancer market is expected to surge in the 7MM from USD 9,730 million in 2017 by 2030.

Audit the market before venturing with DelveInsight’s Due Diligence Services  

About DelveInsight
DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance.  Get hassle-free access to all the healthcare and pharma market research reports through our subscription-based platform PharmDelve.
For more insights, visit Pharma, Healthcare, and Biotech News