Poor Choice of Stroke Patients for EVT; Sluggish Entresto Uptake; CBD for High BP?

German centers report that stroke patients selected for endovascular therapy based on CT criteria did not show benefit over best medical treatment alone. In fact, there were signals of increased bleeding and mortality in the real world. (Stroke)

Physical activity levels were up when people were told to set their own daily step goals as part of a gamification intervention, according to a trial of people at risk of atherosclerotic cardiovascular disease (ASCVD) who were living in lower-income areas of Philadelphia. (JAMA Cardiology)

Continuous monitoring suggests that for every hour less that a person exercises per week, their risk of atrial fibrillation (Afib) onset the next week increases by 25%. (European Heart Journal)

In 5 to 10 years, “I’ll be able to do the same quality of physical exam out of the office as if you were right in front of me in the office,” cardiologist Michael Blum, MD, of University of California San Francisco, said about virtual technology. (Wall Street Journal)

The slow uptake of sacubitril/valsartan (Entresto) was attributed in part to high copays for people on Medicare. (Circulation: Cardiovascular Quality and Outcomes)

The link between certain biomarkers and heart failure was attenuated by intensive blood pressure lowering in the SPRINT trial, a post hoc analysis found. (JAMA Cardiology)

In MESA, high-sensitivity C-reactive protein was key to the link between lipoprotein(a) and ASCVD risk. (Journal of the American College of Cardiology)

Chemotherapy recipients undergoing cardiac resynchronization therapy for anthracycline-induced cardiomyopathy seemed to fare similarly to people with other etiologies of nonischemic cardiomyopathy. (Heart)

Teprasiran, a novel small interfering RNA, reduced early acute kidney injury after cardiac surgery in a phase II trial. (Circulation)

It was active cancer, not a history of cancer, that boded poorly for people undergoing percutaneous coronary intervention for a heart attack. (American Journal of Cardiology)

Opt for a drug-eluting balloon or a drug-eluting stent (DES) for the treatment of DES in-stent restenosis? Outcomes are similar in the long run, Polish registry showed. (Circulation: Cardiovascular Interventions)

Despite a recent drop in radiation exposure during diagnostic cardiac catheterizations across Germany, some outlying sites still haven’t started following low-dose acquisition protocols. (JACC: Cardiovascular Interventions)

FDA approved the OCS Heart System for longer preservation of donor hearts with over 4 hours of cross-clamp times, TransMedics announced. This is in line with votes from a FDA advisory committee in April 2021.

AliveCor maintains that its KardiaMobile 6L device is better at detecting Afib than other personal ECG devices.

Among heart disease patients living in rural areas, those who were not married reported more hopelessness. (Journal of the American Heart Association)

Aspirin use in Europe doesn’t come close to that in the U.S., suggested researchers who surveyed patients of a Baltimore center versus a hospital in Ireland. (Journal of the American College of Cardiology)

Fatty skin lesions on the hands turned out to be the smoking gun for diagnosing homozygous familial hypercholesterolemia in one girl. (JAMA Dermatology)

Can CBD reduce systolic blood pressure? Lexaria says a small trial of its proprietary CBD formulation suggests so.